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Novel and innovative science is paramount to building upon what we already know and taking it one step further.



Research is fundamental to CARF’s mission and has been a top priority since its inception in 2004. CARF is in a unique position to align the resources necessary to provide hope for today and a cure for tomorrow. With a renowned Scientific Advisory Board and generous donors, CARF can offer research grants to those that are meritorious and as funds allow.

Focus
Due to budget constraints this year, CARF is unable to sponsor research grants, but will be convening a cohort of key opinion leaders to discuss future plans. This cohort will be addressing questions like:
  • What is going on in the world of science that holds the most promise for scarring alopecia?
  • What are the obstacles to advancing discoveries for scarring alopecia?
  • What new technologies present the best scenario for collaboration around treatments and research?
  • What ways can CARF help facilitate interactions between science, medicine and patients?
  • Where should CARF use its limited resources to have the biggest impact for our members who are living daily with this condition?
  • What should we realistically strive for in the future?

RELATED INFO

Previously Funded CARF Grants
2016
• Sebaceous gland dysfunction as a driver of scarring alopecia


2015
• Prevalence and risk factors for the development of Cicatricial Alopecia: A population study of hair loss in African American women across the United States

• Lipidomic Analysis of Cicatricial Alopecia Mouse Models


2014
• MicroRNA expression and function in Lichen Planopilaris (LPP)
• Comparative evaluation of the lipidome in sebaceous glands of lichen planopilaris and normal hair follicles


2013
• Endogenous retinoids in the pathogenesis of Cicatrical Alopecia

• Epithelial-mesenchymal transistion (EMT) of human hair follicle epithelial stem cells in situ: Identification of controls that can be targeted to suppress scarring in lichen planopilaris and chronic cutaneous lupus erythematosus

• Cicatricial Alopecia in Tal1 Mutant Mice


2012
• The role of neurogenic inflammation in symptomatic Lichen Planopilaris (LPP)


2011
• Molecular characterization of a novel mouse ENU-induced mutation causing Cicatricial Alopecia with neurophilic infiltrates

• The role of perilipin family of lipid droplet-associated proteins in sebaceous lipogenesis
Utilizing skin lipid profiles to Identify dermatological diseases


2009
• An immunohistochemical study of Central Centrifugal Cicatricial Alopecia (CCCA)


2008
• Role of PPAR gamma regulatory pathways in scarring alopecias

• Characterization of hair follicle bulge immune privilege status in Lichen Planopilaris (LPP)

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